**Chemometrics Methods Development**

We have a long-standing interest in the application of chemometrics methods to high-dimensional (often spectral) datasets. Recent work has focused on methods for assisting in the interpretation and visualization of the results of statistical analyses, such as "IFRNOPLS" ( |

- Tapp H. S., Penfold R. A., Kemsley E. K.(2011)
**Tinylvr: a utility for viewing single predictor multivariate models in terms of a two factor latent vector model**Chemometrics and Intelligent Laboratory Systems 105 19-26 [doi:10.1016/j.chemolab.2010.10.006] - Tapp H. S., Kemsley E. K.(2009)
**Notes on the practical utility of OPLS**Trends in Analytical Chemistry 28 1322-1327 - Kemsley E. K., Tapp H. S.(2009)
**OPLS filtered data can be obtained directly from non-orthogonalized PLS1**Journal of Chemometrics 23 263-264 - Tapp H. S., Kemsley E. K.(2008)
**Optimizing the efficiency of cross-validation in linear discriminant analysis through selective use of the Sherman-Morrison-Woodbury inversion formula**Journal of Chemometrics 22 419-421 - Kemsley E. K.(2001)
**A hybrid classification method: discrete canonical variate analysis using a genetic algorithm**Chemometrics and Intelligent Laboratory Systems 55 39-51 - Defernez M., Kemsley E. K.(1999)
**Avoiding overfitting in the analysis of high-dimensional data with artificial neural networks (ANNs).**The Analyst 124 1675-1681 - Tapp H. S., Kemsley E. K., Wilson R. H., Holley M. L.(1998)
**Image improvement in soft-field tomography through the use of chemometrics**. Measurements in Science Technology 9 592-598 - Kemsley E. K.(1998)
**A genetic algorithm (GA) approach to the calculation of canonical variates (CVs).**Trends in Analytical Chemistry 17 24-34 - Defernez M., Kemsley E. K.(1997)
**The use and misuse of chemometrics for treating classification problems.**Trends in Analytical Chemistry 16 216-221 - Kemsley E. K.(1996)
**Discriminant analysis of high-dimensional data: a comparison of principal components analysis and partial least squares data reduction methods**Chemometrics and Intelligent Laboratory Systems 33 47-61

**Funding**: Our work on methods development has been supported by:

- BBSRC Competitive Strategic Grant (2000 - present)
- MAFF (1997 - 1999)