Campylobacter research at IFR

Members of the Campylobacter research group at IFR

 

Arnoud van Vliet, PhD (CV)
Group Leader, Deputy Programme Leader
email: arnoud.vanvliet@ifr.ac.uk

Arnoud
Bruce Pearson (CV)
Senior Post-doc
Projects: genetic responses, metabolic responses
email: bruce.pearson@ifr.ac.uk
Bruce
Mark Reuter, PhD (CV)
Post-Doc
Projects: stress responses, genetic responses
email: mark.reuter@ifr.ac.uk
Mark
Fran Mulholland, PhD (CV)
Proteomics Partnership
Projects: Proteomics of Campylobacter
email: francis.mulholland@ifr.ac.uk
Fran

 

PhD students at the IFR Campylobacter research group

 

Helen Brown
PhD student
Projects: stress responses
email: helen.brown@ifr.ac.uk
Helen
Rob Green
PhD student
Projects: located at UEA-BIO
email: rob.green@ifr.ac.uk
Rob
Rebecca Handley
PhD student
Projects: stress responses, metabolic responses
email: rebecca.handley@ifr.ac.uk
Rebecca

Thanh Le
PhD student
Projects: host responses, stress responses
email: thanh.le@ifr.ac.uk

Thanh
Frances Shaw
PhD-student
Projects: Polyamine biosynthesis in Campylobacter
email: frances.shaw@ifr.ac.uk
Frances

 

 

Associated with / Former members of the IFR Campylobacter research group

 

Johanna Meier
Former Visiting PhD-student
email:
Johanna
Paula Periago Bayonas, PhD
Former Visiting Scientist
email:
Paula
Duncan Gaskin, PhD
Former member of the group
email: duncan.gaskin@ifr.ac.uk
Duncan
Neil Shearer, PhD
Former member of the group
email: neil.shearer@ifr.ac.uk
Neil
Prof. Mike Peck, PhD
Programme leader, Foodborne Bacterial Pathogens ISP
email: mike.peck@ifr.ac.uk
Mike Peck

 

 

Short curriculum vitea of group members

 

Arnoud H.M. van Vliet

Arnoud van Vliet studied Medical Biology at the University of Utrecht, the Netherlands, where he also completed his PhD thesis in 1995 on the characterization and detection of the important veterinary pathogen Cowdria ruminantium. His postdoctoral training started at the Department of Genetics, Leicester, UK, where he worked on gene regulation in Campylobacter jejuni. In 1998 he was awarded a fellowship from the Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO), and worked from 1998-2000 at the Vrije Universiteit Amsterdam and from 2001 onwards as Lecturer at the Erasmus MC - University Medical Center in Rotterdam, the Netherlands. Here he started a research group focussing on the molecular mechanisms underlying stress adaptation and virulence of members of the genus Helicobacter. In June 2007 he moved to the Institute of Food Research to lead the research on Campylobacter.

Arnoud van Vliet is currently receiving editor of Microbiology (SGM) and FEMS Microbiology Letters, and member of the editorial board of Frontiers in Cellular and Infection Microbiology.

Do a PubMed search for references by Arnoud van Vliet.

 

Bruce M. Pearson

Bruce Pearson is a senior Molecular Microbiologist in the IFR Campylobacter Group, employed fulltime at IFR on Campylobacter for the past eight years. Bruce started his career studying Biochemistry at the University of Edinburgh before moving to the Institute in Norwich at the start up of a yeast group to investigate yeast functional genomics. Bruce was involved in the successful yeast genome-sequencing project: sequencing part of Chromosome III; the first Eukaryotic chromosome to be completely sequenced and then sequencing two regions of chromosome XV to help complete the entire yeast genome. During subsequent EU-funded functional genomics initiatives, EUROFAN and EUROFAN II, he completed two “sixpacks” and developed a number of approaches for gene disruption in yeast. He also created a PCR-based method for DNA fingerprinting yeast, which was patented and is currently the method of choice for strain discrimination used commercially by the National Collection of Yeast cultures (NCYC). With over 26 years in Molecular Biology, Bruce has been central to initiating Campylobacter microarrays at IFR and influential in the strategic development of a dual approach using 2-D proteomics and DNA microarrays to analyse Campylobacter stress responses. Bruce is PI for the active BBSRC research project:  ‘Iron Host acute stress responses and the regulation of C. jejuni virulence in the avian gut, in collaboration with Professor Julian Ketley and Professor Tom Humphrey . Recently, he was a key part of the team, who, in collaboration with Intervet/Schering-Plough Animal Health were able to completely sequence and annotate the genome of Campylobacter jejuni strain 81116 (NCTC11828).

Do a PubMed search for references by Bruce M. Pearson.

 

Mark Reuter

Mark Reuter studied Biochemistry at Sussex University before going on to study for a PhD at the John Innes Centre investigating intra-molecular communication within bacterial two-component regulatory proteins. Following his PhD, he went on to work as a Post-Doctorial scientist at the Institute of Food Research where he currently works. During his time at the IFR, Mark has been involved in work on vaccine delivery, two-component regulation in S. pneumonia and development of gene-expression analysis tools relating to microarrays. Currently, Mark is studying biofilm formation in C. jejuni.

 

Fran Mulholland

Fran Mulholland studied Biological Chemistry at the University of Essex, UK, where he also completed his PhD thesis in 1985 on Kallikrein from the Rat Submandibular Gland and Adipose Tissue. His Post Doctoral Training was in the Biochemistry Department at UCHSC Denver, Colorado, where he worked on enzymatic processing of Substance P by endopeptidases in the rat brain. In 1989, following a period in industry at Microtest Research in York, UK, working on immunoaffinity methods of mycotoxin analysis he joined the Biotechnology and Enzymology Department at the Institute of Food Research in Reading, UK. In 1991 he became Head of the Peptide Biochemistry Group investigating the role of peptidases in Lactic Acid Bacteria starter cultures in their growth and in flavour development in cheese and other fermented foods. In 1997 he transferred to the IFR Norwich Lab and joined the Lactococcal Genetics group before becoming a founding member of the Campylobacter group, focusing on the application of proteomic technology to this microorganism. In 2000 he helped establish the Joint IFR/JIC/UEA Proteomic facility and in 2005 became Head of the Proteomic Partnership at IFR, responsible for providing the infrastructure and expertise to support research using proteomic technologies at IFR. His current research interests include the influence of environmental factors. e.g. oxygen, iron, on campylobacter growth by comparative proteomic techniques; the relationship between transcriptomic, proteomic and metabolomic data; and the application of new proteomic technologies with emphasis on the quantitative fractionation prior to MS-based identifications.

 

Last updated: March 9, 2011