Campylobacter research at IFR

Publications from the IFR Campylobacter research group

(updated January 16, 2012)

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2012

  • Le MT, Porcelli I, Weight CM, Gaskin DJH, Carding SR, van Vliet AHM. Acid-shock of Campylobacter jejuni induces flagellar gene expression and host cell invasion. Eur. J. Microbiol. Immunol., in press (2012)

2011

  • Belzer C, van Schendel BAM, Hoogenboezem T, Kusters JG, Hermans PWM, van Vliet AHM, Kuipers EJ. PerR controls peroxide- and iron-responsive expression of oxidative stress defense genes in Helicobacter hepaticus. Eur. J. Microbiol. Immunol. 1, 215–222 (2011)
  • Hanfrey CC, Pearson BM, Hazeldine S, Lee J, Gaskin DJ, Woster PM, Phillips MA, Michael AJ. An alternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway in the human gut microbiota. J Biol Chem., Epub ahead of print, 24 October 2011
  • Metris A, Reuter M, Gaskin DJH, Baranyi J, van Vliet AHM. In vivo and in silico determination of essential genes of Campylobacter jejuni. BMC Genomics 12:535 (2011) [abstract][pdf]
  • Thomas MT, Shepherd M, Poole RK, van Vliet AHM, Kelly DJ, Pearson BM. Two respiratory enzyme systems in Campylobacter jejuni NCTC 11168 contribute to growth on L-lactate. Environ. Microbiol. 13, 48-61 (2011) [PubMed] [pdf]

2010

  • Gaskin DJH, van Vliet AHM. Random mutagenesis strategies for Campylobacter and Helicobacter species. Methods Mol. Biol. 634, 37-52 (2010) [Pubmed]
  • Guccione E, Hitchcock A, Hall SJ, Mulholland F, Shearer N, van Vliet AHM, Kelly DJ. Reduction of fumarate, mesaconate and crotonate by Mfr, a novel oxygen-regulated periplasmic reductase in Campylobacter jejuni. Environ. Microbiol. 12, 576–591 (2010) [PubMed] [pdf] [supplement]
  • Hitchcock A, Hall SJ, Myers JD, Mulholland F, Jones MA, Kelly DJ. Roles of the twin-arginine translocase and associated chaperones in the biogenesis of the electron transport chains of the human pathogen Campylobacter jejuni. Microbiology 156, 2994-3010 (2010) [Pubmed] [pdf]
  • Reuter M, Mallett A, Pearson BM, van Vliet AHM. Biofilm formation in Campylobacter jejuni is increased under aerobic conditions. Appl. Environ. Microbiol. 76, 2122-2128 (2010) [PubMed] [pdf]
  • Stoof J, Kuipers EJ, Klaver G, van Vliet AHM. An ABC transporter and a TonB ortholog contribute to Helicobacter mustelae nickel and cobalt acquisition. Infect. Immun. 78, 4261-4267 (2010) [PubMed] [pdf]
  • Stoof J, Kuipers EJ, van Vliet AHM. Characterization of NikR-responsive promoters of urease and metal transport genes of Helicobacter mustelae. Biometals 23, 145-159 (2010) [PubMed] [pdf]
  • van Vliet AHM. Next Generation Sequencing of microbial transcriptomes: opportunities and challenges. FEMS Microbiol. Lett. 302, 1–7 (2010) [PubMed] [pdf]

2009

  • Belzer C, Stoof J, Breijer S, Kusters JG, Kuipers EJ, van Vliet AHM. The Helicobacter hepaticus hefA gene is involved in resistance to amoxicillin. Helicobacter 14, 72-79 (2009) [PubMed] [pdf] [supplement]
  • Gaskin DJH, Reuter M, Shearer N, Mulholland F, Pearson BM, van Vliet AHM. Genomics of thermophilic Campylobacter species. Genome Dyn. 6, 91-109 (2009) [PubMed]
  • Holmes K, Tavender TJ, Winzer K, Wells JM, Hardie KR. AI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro. BMC Microbiol. 9, 214 (2009) [PubMed]
  • Mellits KH, Connerton IF, Loughlin MF, Clarke P, Smith J, Dillon E, Connerton PL, Mulholland F, Hawkey CJ. Induction of a chemoattractant transcriptional response by a Campylobacter jejuni boiled cell extract in colonocytes. BMC Microbiol. 9, 28 (2009) [PubMed] [pdf]
  • van Vliet AHM, Wren BW. New levels of sophistication in the transcriptional landscape of bacteria. Genome Biol. 10, 233 (2009) [PubMed] [pdf]
  • van Vliet AHM. Transcriptome profiling by high-throughput sequencing: zooming in on the process of transcription. Biotech Internat. 21, 16-19 (2009) [Journal website]

2008

  • Guccione E, Leon-Kempis MDR, Pearson BM, Hitchin E, Mulholland F, van Diemen PM, Stevens MP, Kelly DJ. Amino-acid dependent growth of Campylobacter jejuni: Key roles for aspartase (AspA) under microaerobic and oxygen-limited conditions and identification of AspB (Cj0762), essential for growth on glutamate. Mol. Microbiol. 69, 77–93 (2008) [PubMed] [pdf] [supplement]
  • Monk CE, Pearson BM, Mulholland F, Smith HK, Poole RK. Oxygen- and NssR-dependent globin expression and enhanced iron acquisition in the response of Campylobacter to nitrosative stress. J. Biol. Chem. 283, 28413-28425 (2008) [PubMed] [pdf] [supplement]
  • Stintzi A, van Vliet AHM, Ketley JM. Iron metabolism, transport and regulation. In Nachamkin I, Szymanski CM, Blaser MJ (eds.), Campylobacter, 3rd Edition, chapter 33, p. 591-610. ASM Press, Washington DC, USA (2008) [information]
  • Stoof J, Belzer C, van Vliet AHM. Metal metabolism and transport in Helicobacter pylori. In Yamaoka Y (ed.), Molecular Genetics of Helicobacter. Caister Academic Press, Norfolk, UK; p. 165-177 (2008) [information]
  • Stoof J, Breijer S, Pot RGJ, van der Neut D, Kuipers EJ, Kusters JG, van Vliet AHM. Inverse nickel-responsive regulation of two urease enzymes in the gastric pathogen Helicobacter mustelae. Environ. Microbiol. 10, 2586–2597 (2008) [PubMed] [pdf] [supplement]

2007

  • Cohn MT, Ingmer H, Mulholland F, Jorgensen K, Wells JM, Brøndsted L. Conserved ATP-dependent proteases of Campylobacter jejuni: The contribution to stress tolerance and virulence. Appl. Environ. Microbiol. 73, 7803-7813 (2007) [PubMed] [pdf]
  • Crossley RA, Gaskin DJH, Holmes K, Mulholland F, Wells J, Kelly DJ, van Vliet AHM, Walton NJ. Riboflavin biosynthesis is associated with assimilatory ferric reduction and iron acquisition by Campylobacter jejuni. Appl. Environ. Microbiol. 73, 7819-7825 (2007) [PubMed] [pdf]
  • Friis LM, Pin C, Taylor DE, Pearson BM, Wells JM. A role for the tet(O) plasmid in maintaining Campylobacter plasticity. Plasmid 57, 18-28 (2007) [PubMed] [pdf]
  • Pearson BM, Gaskin DJH, Segers RPAM, Wells JM, Nuijten PJM, van Vliet AHM. The complete genome sequence of Campylobacter jejuni strain 81116 (NCTC11828). J. Bacteriol. 189, 8402-8403 (2007) [PubMed] [pdf]
  • Pin C, Reuter M. Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approach. BMC Bioinformatics 8, 455 (2007) [PubMed] [pdf]

2006

  • Leon-Kempis MDR, Guccione E, Mulholland F, Williamson MP, Kelly DJ. The Campylobacter jejuni PEB1a adhesin is an aspartate/glutamate-binding protein of an ABC transporter essential for microaerobic growth on dicarboxylic amino acids. Mol. Microbiol. 60, 1262-1275 (2006) [PubMed] [pdf]
  • Pin C, Reuter M, Pearson BM, Overweg K, Baranyi J, Wells JM. Comparison of different approaches for comparative genetic analysis using microarray hybridizations. Appl. Microbiol. Biotech. 72, 852-859 (2006) [PubMed] [pdf]

2005

  • Andersen MT, Brøndsted L, Pearson BM, Mulholland F, Parker M, Pin C, Wells JM, Ingmer H. Diverse roles for HspR in Campylobacter jejuni revealed by the proteome, transcriptome and phenotypic characterization of an hspR mutant. Microbiology 151, 905-915 (2005) [PubMed] [pdf]
  • Brøndsted L, Andersen MT, Parker M, Jørgensen K, Ingmer H. The HtrA protease of Campylobacter jejuni is required for heat and oxygen tolerance and for optimal interaction with human epithelial cells. Appl. Environ. Microbiol. 71, 3205-3212 (2005) [PubMed] [pdf]
  • Friis LM, Pin C, Pearson BM, Wells JM. In vitro cell culture methods for investigating Campylobacter invasion mechanisms. J. Microbiol. Meth. 61, 145-160 (2005) [PubMed] [pdf] [corrigendum]
  • Holmes K, Mulholland F, Pearson BM, Pin C, McNicholl-Kennedy J, Ketley JM, Wells JM. Campylobacter jejuni gene expression in response to iron limitation and the role of Fur. Microbiology 151, 243-257 (2005) [PubMed] [pdf] [supplement]
  • Miller WG, Pearson BM, Wells JM, Parker CT, Kapitonov VV, Mandrell RE. Diversity within the Campylobacter jejuni type I restriction-modification loci. Microbiology 151, 337-351 (2005) [PubMed] [pdf]

2004

  • Batchelor RA, Pearson BM, Friis LM, Guerry P, Wells JM. Nucleotide sequences and comparison of two large conjugative plasmids from different Campylobacter species. Microbiology 150, 3507-3517 (2004) [PubMed] [pdf]
  • Michael I, Slusarenko AJ, Waspi U, Gaskin DJH, Brash AR, Tijet N. Guava (Psidium guajava) 13-hydroperoxide lyase and uses thereof. US patent no. 6,780,621; Aug 24 (2004).

2003

  • Pearson BM, Pin C, Wright J, I'Anson K, Humphrey T, Wells JM. Comparative genome analysis of Campylobacter jejuni using whole genome DNA microarrays. FEBS Lett 554, 224-230 (2003) [PubMed] [pdf]
  • Wells JM, Bennik MHJ. Genomics of food-borne bacterial pathogens. Nutr. Res. Rev. 16, 21-35 (2003) [journal]

Campylobacter papers published by group members prior to joining IFR:

  • Wooldridge KG, van Vliet AHM. Iron Transport and Regulation. In: Ketley JM, Konkel M, eds. Campylobacter: Molecular and Cellular Biology. Norfolk, UK: Horizon Scientific Press; p. 293-310 (2005) [pdf]
  • Matz CM, van Vliet AHM, Ketley JM, Penn CW. Mutational and transcriptional analysis of the Campylobacter jejuni flagellar biosynthesis gene flhB. Microbiology 148, 1679-1685 (2002) [PubMed] [pdf]
  • van Vliet AHM, Ketley JM, Park SF, Penn CW. The role of iron in Campylobacter gene regulation and metabolism. FEMS Microbiol. Rev. 26, 173-186 (2002) [PubMed] [pdf]
  • van Vliet AHM, Baillon MLA, Penn CW, Ketley JM. The iron-induced ferredoxin FdxA of Campylobacter jejuni is involved in aerotolerance. FEMS Microbiol. Lett. 196, 189-193 (2001) [PubMed] [pdf]
  • van Vliet AHM, Ketley JM. Pathogenesis of enteric Campylobacter infection. Symp. Ser. Soc. Appl. Microbiol. 30, 45S-56S (2001) [PubMed] [pdf]
  • Parkhill J, Wren BW, Mungall K, Ketley JM, Churcher C, Basham D, Chillingworth T, Davies RM, Feltwell T, Holroyd S, Jagels K, Karlyshev AV, Moule S, Pallen MJ, Penn CW, Quail MA, Rajandream MA, Rutherford KM, van Vliet AHM, Whitehead S, Barrell BG. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature 403, 665-668 (2000) [PubMed] [pdf] [supplementary table] [supplementary figure]
  • van Vliet AHM, Rock JD, Madeleine LN, Ketley JM. The iron-responsive regulator Fur of Campylobacter jejuni is expressed from two separate promoters. FEMS Microbiol. Lett. 188, 115-118 (2000) [PubMed] [pdf]
  • Baillon MLA, van Vliet AHM, Ketley JM, Constantinidou C, Penn CW. An iron-regulated alkyl hydroperoxide reductase (AhpC) confers aerotolerance and oxidative stress resistance to the microaerophilic pathogen Campylobacter jejuni. J. Bacteriol. 181, 4798-4804 (1999) [PubMed] [pdf]
  • van Vliet AHM, Baillon MLA, Penn CW, Ketley JM. Campylobacter jejuni contains two Fur homologs: characterization of iron-responsive regulation of peroxide stress defense genes by the PerR repressor. J. Bacteriol. 181, 6371-6376 (1999) [PubMed] [pdf]
  • van Vliet AHM, Wood AC, Henderson J, Wooldridge KG, Ketley JM. Genetic manipulation of enteric Campylobacter species. Methods Microbiol 27, 407-419 (1998)
  • van Vliet AHM, Wooldridge KG, Ketley JM. Iron-responsive gene regulation in a Campylobacter jejuni fur mutant. J. Bacteriol. 180, 5291-5298 (1998) [PubMed] [pdf]