Visit the BBSRC website (opens in a new window)

The Institute of Food Research receives strategic funding from BBSRC

  • IFR Home
  • IFR Facts & Figures
  • IFR Science
  • IFR Science for Business
  • Science for Society
  • IFR Publications
  • Latest News from IFR

Biofilm production aids Campylobacter survival

24th March 2010

Scientists at the Institute of Food Research have found a way that the foodborne pathogen Campylobacter can survive in the environment.

Campylobacter is the main cause of food poisoning in Europe and America, most often contracted from eating under-cooked chicken or turkey. It is estimated that there are more than 400,000 cases of Campylobacter food poisoning annually in the UK alone, costing the UK economy an estimated £500 million each year.

Campylobacter cannot survive in the oxygen levels in the air, which forces the bacterium to adapt for survival in the food chain. One such a survival strategy is to form a biofilm, whereby the bacteria stick to a surface and encase themselves in a sticky ‘slime’ which protects them.

In research published in the journal Applied and Environmental Microbiology, IFR researchers have found that Campylobacter will readily form a biofilm under laboratory conditions, and that, when the bacteria were left in air, they respond to these stressful conditions by more rapidly forming this biofilm.  

Campylobacter cells were also shed from the biofilm under environmental conditions, showing that a biofilm is a reservoir of cells that can subsequently enter the food chain, potentially leading to instances of food poisoning.

Campylobacter can clearly sense their stressful environment and try to protect themselves by making a biofilm. Now we need to focus in on those systems that actual sense the stress, in particular, the oxygen sensors” commented Dr. Mark Reuter. 

"While biofilms are well established in the lifestyle and success of other pathogenic bacteria, their role in the lifestyle of Campylobacter was still unclear. We now have developed a model where the biofilm plays a central role in the transmission of Campylobacter via the food chain, and this may lead to new antimicrobial approaches, like disrupting the biofilm matrix or prevention of biofilm formation." commented Dr. Arnoud van Vliet.

By understanding how Campylobacter survives in the environment, this research may suggest novel ways that the food industry can eliminate these bacteria from the food chain or prevent them from entering it at all.

The IFR is an institute of the Biotechnology and Biological Sciences Research Council (BBSRC), and this research, which was funded by the BBSRC, is very timely, as the key UK funders are for the first time developing a joint Campylobacter strategy, a key activity underpinning the Cross Government Research and Innovation Strategy for Food published earlier this year.

About Campylobacter:
Campylobacter is a bacterium that is the most common cause of food poisoning in the UK (over 500,000 cases/year) and in many countries. It is found mainly in poultry but also in red meat, unpasteurised milk and untreated water. Although it does not normally grow in food, it spreads easily, so that only a few bacteria in a piece of undercooked chicken could cause illness. Campylobacter infections do not usually cause vomiting, but diarrhoea can be severe and bloody, with abdominal cramps. Normally the treatment is rest and fluid replacement, with medication only being given for severe cases.

Arnoud van Vliet:

IFR Press Office:

Andrew Chapple, Tel: 01603 251490, email:
Zoe Dunford, Tel: 01603 255111, email:

Notes to Editors:
“Biofilm Formation by Campylobacter jejuni Is Increased under Aerobic Conditions” Applied and Environmental Microbiology Vol 76 No 7 pp 2122-2128 doi:10.1128/AEM.01878-09

About IFR
The mission of the Institute of Food Research ( is to undertake international quality scientific research relevant to food and human health and to work in partnership with others to provide underpinning science for consumers, policy makers, the food industry and academia. It is a company limited by guarantee, with charitable status, grant aided by the Biotechnology and Biological Sciences Research Council (

The Biotechnology and Biological Sciences Research Council (BBSRC) is the UK funding agency for research in the life sciences. Sponsored by Government, BBSRC annually invests around £450M in a wide range of research that makes a significant contribution to the quality of life for UK citizens and supports a number of important industrial stakeholders including the agriculture, food, chemical, healthcare and pharmaceutical sectors. BBSRC carries out its mission by funding internationally competitive research, providing training in the biosciences, fostering opportunities for knowledge transfer and innovation and promoting interaction with the public and other stakeholders on issues of scientific interest in universities, centres and institutes.

The Babraham Institute, Institute for Animal Health, Institute of Food Research, John Innes Centre and Rothamsted Research are Institutes of BBSRC. The Institutes conduct long-term, mission-oriented research using specialist facilities. They have strong interactions with industry, Government departments and other end-users of their research.

Share this page: