Arjan Narbad
Research Leader
Research Area: Integrated Biology of GI Tract
Contact Details:
Institute of Food Research,
Norwich Research Park,
Colney, Norwich,
NR4 7UA
UK
arjan.narbad@ifr.ac.uk
Research interests
My research interests are focused on the isolation and characterisation gut commensal bacteria of animal and human origin for use as probiotics for exclusion of food-borne pathogens and in elucidation of the role of commensal bacteria in the health of humans and animals. The effect of dietary components on the gut microbial ecology as well as the importance of gut bacteria in transformation of bioactive molecules are being studied in human volunteers and in vitro using model gut systems. Mechanism of competitive exclusion phenomena is being investigated with the objective of strain improvements.
Selected Publications
Noor S. O., Ridgway K., Scovell L., Kemsley E. K., Lund E. K., Crawford J., Johnson I. T., Narbad A. (2010)
Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota
BMC Gastroenterology 10 134
Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota
BMC Gastroenterology 10 134
Oguntoinbo F., Tourlomousis P., Gasson M. J., Narbad A. (2010)
Analysis of microbial communities of traditional fermented West African cereal foods using culture independent methods
International Journal of Food Microbiology 145 (1) 205-210
Analysis of microbial communities of traditional fermented West African cereal foods using culture independent methods
International Journal of Food Microbiology 145 (1) 205-210
Rahman L., Kouno H., Hashiguchi Y., Yamamoto H., Narbad A., Parr A., Walton N. J., Ikenaga T., Kitamura Y. (2009)
HCHL expression in hairy roots of Beta vulgaris yields a high accumulation of p-hydroxybenzoic acid (pHBA) glucose ester, and linkage of pHBA into cell walls
Bioresource Technology 100 (20) 4836-4842
HCHL expression in hairy roots of Beta vulgaris yields a high accumulation of p-hydroxybenzoic acid (pHBA) glucose ester, and linkage of pHBA into cell walls
Bioresource Technology 100 (20) 4836-4842
Wegmann U., Overweg K., Horn N., Goesmann A., Narbad A., Gasson M., Shearman C. (2009)
The complete genome sequence of lactobacillus johnsonii fi9785, a competitive exclusion agent against pathogens in poultry
Journal of Bacteriology 191 (22) 7142-7143
The complete genome sequence of lactobacillus johnsonii fi9785, a competitive exclusion agent against pathogens in poultry
Journal of Bacteriology 191 (22) 7142-7143
Recent Publications
Le Gall G., Noor S., Ridgway K., Scovell L., Crawford J., Johnson I. T., Colquhoun I. J., Kemsley E. K., Narbad A. (2011)
Metabolomics of faecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome
Journal of Proteome Research 10 (9) 4208-4218
Metabolomics of faecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome
Journal of Proteome Research 10 (9) 4208-4218
Mayer M. J., Garefaliki V., Spoerl R., Narbad A., Meijers R. (2011)
Structure-based modification of a Clostridium difficile-targeting endolysin affects activity and host range
Journal of Bacteriology 193 (19) 5477-5486
Structure-based modification of a Clostridium difficile-targeting endolysin affects activity and host range
Journal of Bacteriology 193 (19) 5477-5486
Nueno Palop C., Narbad A. (2011)
Probiotic assesment of Enterococcus faecalis CP58 isolated during an in vitro screening of lactic acid bacteria.
International Journal of Food Microbiology 145 (2-3) 390-394
Probiotic assesment of Enterococcus faecalis CP58 isolated during an in vitro screening of lactic acid bacteria.
International Journal of Food Microbiology 145 (2-3) 390-394
Meader E., Mayer M. J., Gasson M. J., Steverding D., Carding S. R., Narbad A. (2010)
Bacteriophage treatment significantly reduces viable Clostridium difficile and prevents toxin production in an in vitro model system
Anaerobe 16 (6) 549-554
Bacteriophage treatment significantly reduces viable Clostridium difficile and prevents toxin production in an in vitro model system
Anaerobe 16 (6) 549-554
Mandalari G., Faulks R. M., Bisignano G., Waldron K. W., Narbad A., Wickham M. S. J. (2010)
In vitro evaluation of the prebiotic properties of almond skins (amygdalus communis l.)
FEMS Microbiology Letters 304 (2) 116-122
In vitro evaluation of the prebiotic properties of almond skins (amygdalus communis l.)
FEMS Microbiology Letters 304 (2) 116-122
Mandalari G., Tomaino A., Bisignano G., Narbad A., Waldron K. W., Wickham M. S. J. (2010)
Prebiotic potential and antimicrobial effect from a by-product of the almond processing industry
Total Food: Sustainability of the Agri-Food Chain
RSC Books, Cambridge
(Value added products - Plants) 86-89
Prebiotic potential and antimicrobial effect from a by-product of the almond processing industry
Total Food: Sustainability of the Agri-Food Chain
RSC Books, Cambridge
(Value added products - Plants) 86-89
Mayer M. J., Payne J., Gasson M. J., Narbad A. (2010)
Genomic sequence and characterisation of the virulent bacteriophage φCTP1 from clostridium tyrobutyricum
Applied and Environmental Microbiology 76 (16) 5415-5422
Genomic sequence and characterisation of the virulent bacteriophage φCTP1 from clostridium tyrobutyricum
Applied and Environmental Microbiology 76 (16) 5415-5422
Swiatecka D., Narbad A., Ridgway K., Kostyra H. (2010)
The study on the impact of glycated pea proteins on human intestinal bacteria (correction published in 2011, see notes field)
International Journal of Food Microbiology 145 (1) 267-272
The study on the impact of glycated pea proteins on human intestinal bacteria (correction published in 2011, see notes field)
International Journal of Food Microbiology 145 (1) 267-272
Tourlomousis P., Kemsley E. K., Ridgway K. P., Toscano M. J., Humprey T. J., Narbad A. (2010)
PCR-denaturing gradient gel electrophoresis of complex microbial communities: a two-step approach to address the effect of gel-to-gel variation and allow valid comparisons across a large data set
Microbial Ecology 59 (4) 776-786
PCR-denaturing gradient gel electrophoresis of complex microbial communities: a two-step approach to address the effect of gel-to-gel variation and allow valid comparisons across a large data set
Microbial Ecology 59 (4) 776-786
Trombetta D., Cimino F., Cristani M., Mandalari G., Saija A., Ginestra G., Speciale A., Chirafisi J., Bisignano G., Narbad A., Faulds C. B., Waldron K. W. (2010)
In vitro protective effects of two extracts from bergamot peels on human endothelial cells exposed to tumor necrosis factor (TNF-alpha)
Journal of Agricultural and Food Chemistry 58 (14) 8430-8436
In vitro protective effects of two extracts from bergamot peels on human endothelial cells exposed to tumor necrosis factor (TNF-alpha)
Journal of Agricultural and Food Chemistry 58 (14) 8430-8436
Fax: +44(0)1603 507723 
