Arjan Narbad
Senior Scientist
Research Area: Integrated Biology of GI Tract
Contact Details:
Institute of Food Research,
Norwich Research Park,
Colney, Norwich,
NR4 7UA
UK
arjan.narbad@bbsrc.ac.uk
Research interests
My research interests are focused on the isolation and characterisation gut commensal bacteria of animal and human origin for use as probiotics for exclusion of food-borne pathogens and in elucidation of the role of commensal bacteria in the health of humans and animals. The effect of dietary components on the gut microbial ecology as well as the importance of gut bacteria in transformation of bioactive molecules are being studied in human volunteers and in vitro using model gut systems. Mechanism of competitive exclusion phenomena is being investigated with the objective of strain improvements.Selected Publications
Rahman L., Kouno H., Hashiguchi Y., Yamamoto H., Narbad A., Parr A., Walton N. J., Ikenaga T., Kitamura Y. (2009)
HCHL expression in hairy roots of Beta vulgaris yields a high accumulation of p-hydroxybenzoic acid (pHBA) glucose ester, and linkage of pHBA into cell walls
Bioresource Technology 100 (20) 4836-4842
HCHL expression in hairy roots of Beta vulgaris yields a high accumulation of p-hydroxybenzoic acid (pHBA) glucose ester, and linkage of pHBA into cell walls
Bioresource Technology 100 (20) 4836-4842
Wegmann U., Overweg K., Horn N., Goesmann A., Narbad A., Gasson M., Shearman C. (2009)
The complete genome sequence of lactobacillus johnsonii fi9785, a competitive exclusion agent against pathogens in poultry
Journal of Bacteriology 191 (22) 7142-7143
The complete genome sequence of lactobacillus johnsonii fi9785, a competitive exclusion agent against pathogens in poultry
Journal of Bacteriology 191 (22) 7142-7143
Recent Publications
Mandalari G., Faulks R. M., Bisignano G., Waldron K. W., Narbad A., Wickham M. S. J. (2010)
In vitro evaluation of the prebiotic properties of almond skins (amygdalus communis l.)
FEMS Microbiology Letters 304 (2) 116-122
In vitro evaluation of the prebiotic properties of almond skins (amygdalus communis l.)
FEMS Microbiology Letters 304 (2) 116-122
Mandalari G., Tomaino A., Bisignano G., Narbad A., Waldron K. W., Wickham M. S. J. (2010)
Prebiotic potential and antimicrobial effect from a by-product of the almond processing industry
Total Food: Sustainability of the Agri-Food Chain
RSC Books, Cambridge
(Value added products - Plants) 86-89
Prebiotic potential and antimicrobial effect from a by-product of the almond processing industry
Total Food: Sustainability of the Agri-Food Chain
RSC Books, Cambridge
(Value added products - Plants) 86-89
Tourlomousis P., Kemsley E. K., Ridgway K. P., Toscano M. J., Humprey T. J., Narbad A. (2010)
PCR-denaturing gradient gel electrophoresis of complex microbial communities: a two-step approach to address the effect of gel-to-gel variation and allow valid comparisons across a large data set
Microbial Ecology 59 (4) 776-786
PCR-denaturing gradient gel electrophoresis of complex microbial communities: a two-step approach to address the effect of gel-to-gel variation and allow valid comparisons across a large data set
Microbial Ecology 59 (4) 776-786
Trombetta D., Cimino F., Cristani M., Mandalari G., Saija A., Ginestra G., Speciale A., Chirafisi J., Bisignano G., Narbad A., Faulds C. B., Waldron K. W. (2010)
In vitro protective effects of two extracts from bergamot peels on human endothelial cells exposed to tnf-alpha
Journal of Agricultural and Food Chemistry
In vitro protective effects of two extracts from bergamot peels on human endothelial cells exposed to tnf-alpha
Journal of Agricultural and Food Chemistry
Fernandez A., Horn N., Wegmann U., Nicoletti C., Gasson M. J., Narbad A. (2009)
Enhanced secretion of biologically active murine interleukin-12 by Lactococcus lactic
Applied and Environmental Microbiology 75 (3) 869-871
Enhanced secretion of biologically active murine interleukin-12 by Lactococcus lactic
Applied and Environmental Microbiology 75 (3) 869-871
Ginestra G., Parker M. L., Bennett R. N., Robertson J., Mandalari G., Narbad A., Lo Curto R. B., Bisignano G., Faulds C. B., Waldron K. W. (2009)
Anatomical, chemical and biochemical characterization of cladodes from prickly pear (Opuntia ficus-indica L. Mill)
Journal of Agricultural and Food Chemistry 57 (21) 10323-10330
Anatomical, chemical and biochemical characterization of cladodes from prickly pear (Opuntia ficus-indica L. Mill)
Journal of Agricultural and Food Chemistry 57 (21) 10323-10330
Mandalari G., Rich G. T., Faulks R. M., Bisignano C., Narbad A., Wickham M. S. J. (2009)
Almonds demonstrate prebiotic potential. Effects of almond lipid on colonic microbiota
Agro FOOD Industry Hi Tech 20 (3) 14-16
Almonds demonstrate prebiotic potential. Effects of almond lipid on colonic microbiota
Agro FOOD Industry Hi Tech 20 (3) 14-16
Moon G., Wegmann U., Gunning A. P., Gasson M. J., Narbad A. (2009)
Isolation and characterization of a theta-type cryptic plasmid from Bifidobacterium longum FI10564
Journal of Microbiology and Biotechnology 19 ((4)) 403–408
Isolation and characterization of a theta-type cryptic plasmid from Bifidobacterium longum FI10564
Journal of Microbiology and Biotechnology 19 ((4)) 403–408
Harrington C. R., Lucchini S., Ridgway K. P., Wegmann U., Eaton T. J., Hinton J. C. D., Gasson M. J., Narbad A. (2008)
A short-oligonucleotide microarray that allows improved detection of gastrointestinal tract microbial communities
BMC Microbiology 8 (1) 195
DOI:doi:10.1186/1471-2180-8-195
A short-oligonucleotide microarray that allows improved detection of gastrointestinal tract microbial communities
BMC Microbiology 8 (1) 195
DOI:doi:10.1186/1471-2180-8-195
Mandalari G., Nueno-Palop C., Bisignano G., Wickham M. S. J., Narbad A. (2008)
Investigation of the potential prebiotic properties of almond (Amygdalus communis L.) seeds
Applied and Environmental Microbiology 74 (14) 4264-4270
Investigation of the potential prebiotic properties of almond (Amygdalus communis L.) seeds
Applied and Environmental Microbiology 74 (14) 4264-4270
Mayer M. J., Narbad A., Gasson M. J. (2008)
Molecular characterisation of a Clostridium difficile bacteriophage and its cloned biologically active endolysin
Journal of Bacteriology 190 (20) 6734-6740
Molecular characterisation of a Clostridium difficile bacteriophage and its cloned biologically active endolysin
Journal of Bacteriology 190 (20) 6734-6740
Narbutaite V., Ferrnandez A., Horn N., Juodeikiene G., Narbad A. (2008)
Influence of baking enzymes on antimicrobial activity of five bacteriocin-like inhibitory substances produced by lactic acid bacteria isolated from Lithuanian sourdoughs
Letters in Applied Microbiology 47 (6) 555-560
Influence of baking enzymes on antimicrobial activity of five bacteriocin-like inhibitory substances produced by lactic acid bacteria isolated from Lithuanian sourdoughs
Letters in Applied Microbiology 47 (6) 555-560
Parisot J. J., Carey S., Breukink E., deKruijff B., Chan W. C., Narbad A., Bonev B. (2008)
Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic
Antimicrobial Agents & Chemotherapy 52 612-618
Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic
Antimicrobial Agents & Chemotherapy 52 612-618
Vardakou M., Nueno-Palop C., Christakopoulos P., Gasson M. J., Narbad A. (2008)
Evaluation of the prebiotic properties of wheat arabinoxylan fractions and induction of hydrolase activity in gut microflora
International Journal of Food Microbiology 123 166-170
Evaluation of the prebiotic properties of wheat arabinoxylan fractions and induction of hydrolase activity in gut microflora
International Journal of Food Microbiology 123 166-170
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