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Fran Mulholland

Senior Research Associate

Research Area: Proteomics

Contact Details:

Institute of Food Research,
Norwich Research Park,
Colney, Norwich,
NR4 7UA
UK
francis.mulholland@ifr.ac.uk

Research interests

  • comparative proteomic analysis of campylobacter, in particularly the influence of environmental factors. e.g. oxygen, iron, on strain variation and growth.
  • the relationship between transcriptomic, proteomic and metabolomic data.
  • the application of proteomic technology in the laboratory with emphasis on the quantitative fractionation of samples prior to ms-based identification procedures.

Recent Publications

Bouwman F. G., de Roos B., Rubio-Aliaga I., Crosley L. K., Duthie S. J., Mayer C., Horgan G., Polley A. C., Heim C., Coort S. L. M., Evelo C., Mulholland F., Johnson I. T., Elliott R. K., Daniel H., Mariman C. M. (2011)
TwoD-electrophoresis and multiplex immunoassay proteomicanalysis of different body fluids and cellular components revealknown and novel markers for prolonged fasting.
BMC Medical Genomics 4 24
Hockin N. L., Mulholland F., Mock T., Kopriva S., Malin G. (2011)
The response of diatom central carbon metabolism to nitrogen starvation is different to that of green algae and higher plants
Plant Physiology 158 (1) 299-312
DOI:10.1104/pp.111.184333
Rubio-Aliaga I., de Roos B., Duthie S. J., Crosley L. K., Mayer C., Horgan G., Colquhoun I. J., Le Gall G., Huber F., Kremer W., Rychlik M., Wopereis S., van Ommen B., Schmidt G., Heim C., Bouwman F. G., Mariman E. C., Mulholland F., Johnson I. T., Polley A. C., Elliott R. M., Daniel H. (2011)
Metabolomics of prolonged fasting in humans reveals new catabolic markers
Metabolomics 7 (3) 375-387
Vardakou M., Sainsbury F., Rigby N. M., Mulholland F., Lomonossoff G. P. (2011)
Expression of active recombinant human gastric lipase in Nicotiana benthamiana using the CPMV-HT transient expression system
Protein Expression and Purification 81 (1) 69-74
DOI:10.1016/j.pep.2011.09.005
Guccione E., Hitchcock A., Hall S. J., Mulholland F., Shearer N., van Vliet A. H. M., Kelly D. J. (2010)
Reduction of fumarate, mesaconate and crotonate by Mfr, a novel oxygen-regulated periplasmic reductase in Campylobacter jejuni
Environmental Microbiology 12 (3) 576-591
DOI:10.1111/j.1462-2920.2009.02096.x
Hitchcock A., Hall S. J., Myers J. D., Mulholland F., Jones M. A., Kelly D. J. (2010)
Roles of the twin-arginine translocase and associated chaperones in the biogenesis of the electron transport chains of the human pathogen Campylobacter jejuni
Microbiology-SGM 156 2994-3010

 
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