Thomas Wilhelm

Senior Scientist

Research Area: Theoretical Systems Biology

Contact Details:

Institute of Food Research,
Norwich Research Park,
Colney, Norwich,
NR4 7UA
UK
thomas.wilhelm@bbsrc.ac.uk

Research interests

integration and statistical analysis of biological data; dynamical modelling of biological systems; analysis of biological networks; chemoinformatics

Selected Publications

Hollunder J., Friedel M., Kuiper M., Wilhelm T. (2010)
DASS-GUI: a user interface for identification and analysis of significant patterns in non-sequential data
Bioinformatics 26 (7) 987-989
DOI:10.1093/bioinformatics/btq071

Friedel M., Nikolajewa S., Suehnel J., Wilhelm T. (2009)
DiProGB: the dinucleotide properties genome browser
Bioinformatics 25 2603-2604
DOI:10.1093/bioinformatics/btp436

Wilhelm T. (2009)
The smallest chemical reaction system with bistability
BMC Systems Biology 3 90

Recent Publications

Aho T., Almusa H., Matilainen J., Larjo A., Ruusuvuori P., Aho K. L., Wilhelm T., Lähdesmäki H., Beyer A., Harju M., Chowdhury S., Leinonen K., Roos C., Yli-Harja O. (2010)
Reconstruction and validation of RefRec: a global model for the yeast molecular interaction network.
PLoS One 5 (5) e10662
DOI:10.1371/journal.pone.0010662

Lorenz P., Dietmann S., Wilhelm T., Koczan D., Autran S., Gad S., Wen G., Ding G., Li Y., Rousseau-Merck M. F., Thiesen H. J. (2010)
The ancient mammalian krab zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of c2h2 zinc finger evolution associated with unique expression profiles in human tissues.
BMC Genomics 11 206
DOI:doi:10.1186/1471-2164-11-206

Friedel M., Nikolajewa S., Suehnel J., Wilhelm T. (2009)
DiProDB: a database for dinucleotide properties
Nucleic Acids Research 37 (Special Issue S1) D37-D40

Behre J., Wilhelm T., von Kamp A., Ruppin E., Schuster S. (2008)
Structural robustness of metabolic networks with respect to multiple knockouts
Journal of Theoretical Biology 252 433–441

Friedel M., Nikolajewa S., Wilhelm T. (2008)
The decomposition tree for analyses of boolean functions
Mathematical Structures in Computer Science 18 (2) 411-426

Kim J. , Wilhelm T. (2008)
What is a complex graph?
Physica A 387 2637-2652