Prof. Arjan Narbad
WebsiteFood Safety Centre
My research interests are focused on the microbial ecology of the gastrointestinal tract and the role of the complex gut microbiota in health and disease.
I have a particular interest in the isolation and characterisation of gut commensal bacteria of animal and human origin for use as probiotics for exclusion of gut pathogens. Mechanisms of competitive exclusion phenomena are being investigated with the objective of designing strains with improved functionality.
I am interested in identifying and characterising novel antimicrobials (including bacteriophage endolysins) that target gut pathogens such as Clostridium difficile and Clostridium perfringens, and the impact of these biomolecules on the gut microbial communities is another area of active research within my group.
The effect of dietary components on the gut microbial ecology and the importance of gut commensals in transformation of food bioactive molecules are being studied using in vitro model gut systems as well in vivo with human volunteers.
Molecular metabolism (2016) 1 6 p1-6
Publisher’s version: doi:10.1016/j.molmet.2016.06.006
Lipid Technology 27 p179-182
Publisher’s version: 10.1002/lite.201500035
Anaerobe 33 p90-97
Publisher’s version: doi:10.1016/j.anaerobe.2015.02.006
Identification of Proteins Possibly Involved in Glucosinolate Metabolism in L. agilis R16 and E. coli VL8.
The proteome Journal 34 p135-46
Publisher’s version: 10.1007/s10930-015-9607-0
Impact of the exopolysaccharide layer on biofilms, adhesion and resistance to stress in Lactobacillus johnsonii FI9785.
BMC Microbiology 15 p8
Publisher’s version: 10.1186/s12866-015-0347-2
Microbial Ecology in Health and Disease (MEHD) 26 p26050
Publisher’s version: 10.3402/mehd.v26.26050
Nutrients 7 p552-71
Publisher’s version: 10.3390/nu7010552
A treatment programme for Clostridium difficile (C.diff) is being announced this week during International Infection Prevention Awareness Week 17-21 October.more +
A collaboration between the NNUH and IFR has been crucial to the success of the Faecal Microbiota Transplants (FMT) to combat Clostridium difficile infectionmore +
The Institute of Food Research and Jiangnan University have collaborated to initiate a UK-China Joint Centre for Probiotic Research.more +
Research has revealed how viruses called bacteriophages destroy the bacterium Clostridium difficile, which is becoming a serious problem in hospitals and healthcare institutes, due to its resistance to antibiotics.more +
IFR researchers have characterised the coat of a potential poultry probiotic, giving the first clues of how it may be used to exclude pathogenic bacteria from chickens.more +