Dr Lindsay Hall
WebsiteFood Safety Centre
I'm a Research Leader at the Institute of Food Research and a lecturer at the Norwich Medical School at University of East Anglia (UEA).
In 2013 I was awarded a 5 year Wellcome Trust New Investigator Award and am studying the role of early life gut microbiota in resistance to enteric (gut) infections. My research focuses on one of the major early life bacterial groups, bifidobacteria.
The aim is to understand how these pioneer bifidobacteria colonise the gut (via their surface molecules) and subsequently modulate critical resistance to gut infection, and to understand how early life antibiotic-induced disturbances alter this microbial community, ultimately leading to a breakdown in pathogen protection.
Another key goal is to identify bifidobacterial communities that can restore a disturbed early life microbiota back into one able to control gut infection. Gaining further knowledge about these pioneer bifidobacteria may provide a powerful therapeutic focus in infectious and chronic inflammatory disease settings.
Bifidobacterium breve reduces apoptotic epithelial cell shedding in an exopolysaccharide and MyD88-dependent manner.
Open biology 7 p160155
Publisher’s version: 10.1098/rsob.160155
Scientists at the Institute of Food Research (IFR) have uncovered a new mechanism linking bacteria in the gut to Inflammatory Bowel Disease (IBD).more +
A Norwich Research Park scientist has received £1.3 million in funding from the Wellcome Trust to investigate how beneficial bacteria protect against deadly infection in early life.more +
2011-current Lecturer and Research Leader in Gastrointestinal Sciences, Norwich Medical School, University East Anglia, Norwich Research Park, Norwich.
2011-current Research Leader, Institute of Food Research, Norwich Research Park, Norwich.
2007 – 2011 Post Doctoral Research Fellow, Alimentary Pharmabiotic Centre, Biosciences Institute, University College Cork, Cork, Ireland.
2003 – 2007: Ph.D, University of Cambridge. The Wellcome Trust Sanger Institute, Hinxton, Cambridge.
1999 – 2003: BSc (Hons), Microbiology, University of Glasgow.