Prof. Richard Mithen
WebsiteFood and Health Programme
I am the interim director of IFR and I also lead the Food and Health programme. My own research interests are in how diets rich in cruciferous vegetables, such as broccoli, can reduce the risk of certain cancers and cardiovascular disease.
Accumulation of palmitoylcarnitine and its effect on pro-inflammatory pathways and calcium influx in prostate cancer
Publisher’s version: 10.1002/pros.23222
Biosynthesis and Accumulation of Sulphur Compounds in white radish during the first three days of spouting
Bulletin UASVM Food Science and Technology 2 p72
Publisher’s version: 10.15835/buasvmcn-fst:11468
BJU International 115 p69-70
Publisher’s version: 000354476900146
Genome Research 25 p814-824
Publisher’s version: 10.1101/gr.190470.115
Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials.
Molecular Nutrition and Food Research 59 p918-26
Publisher’s version: 10.1002/mnfr.201400863
Proceedings of the Nutrition Society 74 p191
Publisher’s version: 10.1017/S0029665115002177
Osteoarthritis and cartilage 23 p339
Publisher’s version: n/a
Journal of inflammation 12 p6
Publisher’s version: none
Suppression of LPS-induced transcription and cytokine secretion by the dietary isothiocyanate sulforaphane.
Molecular Nutrition and Food Research 58 (12) p22862296
Publisher’s version: 10.1002/mnfr.201400550
Sunday’s BBC Countryfile programme on October 25 included a feature on a variety of broccoli bred to contain higher levels of a compound called glucoraphanin.
Research from human trials with 130 volunteers published earlier this year, showed that including this broccoli in the diet for 12 weeks reduced the levels of LDL-cholesterol by an average of about 6%.more +
Including a new broccoli variety in the diet reduces blood cholesterol levels by around 6%, according to the results of human trials led by the Institute of Food Research.more +
If you are aged 18-50 and live within 40 miles of Norwich, then we need your help on the ‘Effects of Brassica on human gut Lactobacilli’ study.more +
Beneforté superbroccoli has been conventionally bred to contain 2-3 times the levels of naturally occurring compound called glucoraphanin, and has been developed by British science at the Institute of Food Research and the John Innes Centre. Research suggests this could help to maintain cardiovascular health and to reduce the risk of some forms of cancer.more +
Researchers at the Institute of Food Research have obtained the first evidence from human studies of how diets rich in glucosinolates, such as glucoraphanin found in broccoli, can ‘re-tune’ cellular processes that get disrupted as we age.more +