Dr Rob Kingsley
WebsiteFood Safety Centre
The Kingsley lab studies the variation in genotype and phenotype of food-borne bacterial pathogens and their host.
Variation data is used to study the molecular epidemiology of infection and to generate testable hypotheses aimed at understanding the molecular basis of the host-pathogen interaction. With a principal interest in the foodborne pathogen Salmonella enterica, the Kingsley lab combines genomic data, transcriptomic data and other ‘omics data to generate hypotheses that are then tested using classical molecular biology and models of infection.
The long-term aim of this research is to identify targets for novel intervention strategies aimed at decreasing the burden of food-borne disease.
Emerging Infectious Diseases 22 p617-24
Publisher’s version: 10.3201/eid2204.150531
Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host
Nature Microbiology Nature Microbiology 1, Article number: 15023 pNature Microbiology 1, Article number: 15023
Publisher’s version: doi:10.1038/nmicrobiol.2015.23
Phylogeny, resistome and mobile genetic elements of emergent OXA-48 and OXA-245 Klebsiella pneumoniae clones circulating in Spain.
Journal of Antimicrobial Chemotherapy 71 p887-96
Publisher’s version: 10.1093/jac/dkv458
Soluble flagellin coimmunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokine production.
European Journal of Immunology 45 p2299-311
Publisher’s version: 10.1002/eji.201545564
Ceftriaxone-Resistant Salmonella enterica Serotype Typhimurium Sequence Type 313 from Kenyan Patients Is Associated with the blaCTX-M-15 Gene on a Novel IncHI2 Plasmid.
Antimicrobial Agents & Chemotherapy 59 p3133-9
Publisher’s version: 10.1128/AAC.00078-15
Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events.
Nature Genetics 11 p2342
Publisher’s version: 10.1038/ng.3281
A new study has shown how Salmonella rapidly “microevolves” during an epidemic, highlighting how whole genome sequencing is important in tracking pathogenic bacteria.more +
To mark World Health Day's focus on safe food, Dr Rob Kingsley talks about his research into Salmonellamore +
The Institute of Food Research is pleased to welcome Dr Rob Kingsley as a new research leader in its Gut Health and Food Safety programme. Rob’s interests are in understanding how bacteria interact with the host, how they move through the food chain and how they cause disease.more +