• DNA microarrays and global gene expression patterns
• Genomic indexing of Salmonella and E.coli
• Salmonella virulence gene expression during infectionLag Phase
• Salmonella Infection of Chicken oviduct (SafeHouse)
• Influence of Commensal flora, immune response and behaviour on Salmonella infection (VTRI104)
• Environmental regulation of the invasion and intracellular virulence gene programmes of Salmonella: a ppGpp dependent switch

• Regulation of Salmonella SPI1 & SPI2
• Bacterial nitrate metabolism in colonisation of the mammalian gastrointestinal tract
• Analysis of factors affecting Salmonella contamination of meat during the slaughter process (Biotracer)

• "Non genetic variation" gene expression within bacterial populations (Finished)

• Nucleoid associated proteins: DNA topology and gene expression.
• Acambis project on enterotoxigenic E.coli (Finished)

BioTracer

Main Researcher: Gitte Knudsen

Salmonella areimportant zoonotic pathogens of great health and economic importance. Faecal contamination during slaughter of animals is virtually inevitable. However, to pose a threat to food safety Salmonella has to survive the passage through the food chain from animal to consumer. We will use the IFR Gel Cassette as a model food system to mimic growth of Salmonella in meat environments to examine the transcriptomic and physiological responses that facilitate survival in the food chain.
                                                     

BIOTRACER is an EU IP and is co-ordinated by Jeffrey Hoorfar at the National Food Institute, Technical University of Denmark. The objective of BIOTRACER is to improve traceability of microorganisms in the animal feed and food chain. Further information can be found at www.biotracer.org