IFR

Theoretical Systems Biology

 

 

 

 

 

 

 

Thomas Wilhelm

Theoretical Systems Biology
Institute of Food Research
Norwich Research Park
Colney
Norwich NR4 7UA
U.K.

Tel:    +44 (0)1603 255313
Email: thomas.wilhelm@ifr.ac.uk

That's me.

         

 

 


"Enthusiasm always and necessarily prevails over those who are not enthusiastic."

JG Fichte

(Es siegt immer und notwendig die Begeisterung ueber den, der nicht begeistert ist.)

 

Research Interests

BBSRC (Biotechnology and Biological Sciences Research Council), our main funder, defines mathematical biology as ‘embracing bioinformatics, modelling and statistics’. We are active on all three of these areas, especially systems biology, omics data integration and analysis, as well as dynamic modelling.

CV

Diploma (M.Sc.): Biophysics, Humboldt-University Berlin (1992)
Ph.D.: Theoretical Biophysics (Supervisor: Reinhard Heinrich), Humboldt-University Berlin (1997)
Postdoc 1: Institute of Physics (Chair: Peter Hänggi), University of Augsburg (1997-1999)
Postdoc 2: Institute of Freshwater Ecology (IGB), Berlin (1999-2002)
Junior research group leader: Fritz-Lipman Institute of Age Research (FLI), Jena (2002-2007)
Research leader: Institute of Food Research (IFR), Norwich (2007-present)

Editorial

Journal Referee: Advances in Complex Systems, AI Communications, Annalen der Physik, Bioinformatics, BioSystems, BMC Bioinformatics, BMC Evolutionary Biology, BMC Research Notes, BMC Systems Biology, Cell Biochemistry and Biophysics, Complexity, Ecological Modelling, Gene, Genome Biology, IET Systems Biology, Journal of Mathematical Chemistry, Journal of Molecular Evolution, Journal of Theoretical Biology, Molecular Microbiology, Molecular Systems Biology, Physica A,  Physical Review E, Physical Review Letters, PLoS Computational Biology, PLoS One, Proceedings of The Royal Society B, Wiley Interdisciplinary Reviews: Systems Biology and Medicine 
Grant Referee: Biotechnology and Biological Sciences Research Council (BBSRC, UK), Centre Européen de Calcul Atomique et Moléculaire (CECAM, Switzerland), Deutsche Forschungsgemeinschaft (DFG, Germany), Dutch National Science Foundation (NOW, Netherlands), Icelandic Centre for Research
Conference program committees 

Tools

  • DiProGB     - a genome browser considering physical properties of nucleic acids.
  • DASS-GUI - a user interface for data mining (and biclustering).

Selected Publications

  • J. Kim, T. Wilhelm. Spanning tree separation reveals community structure in networksPhys. Rev. E 87 (2013) 032816.
  • J. Hollunder, M. Friedel, M. Kuiper, T. Wilhelm. DASS-GUI: a user interface for identification and analysis of significant patterns in non-sequential data. Bioinformatics 26 (2010) 987-989.
  • T. Wilhelm. The smallest chemical reaction system with bistability. BMC  Systems Biology 3 (2009) 90. Origin of life.
  • M. Friedel, S. Nikolajewa, J. Sühnel, T. Wilhelm. DiProGB: the dinucleotide properties genome browser. Bioinformatics 25 (2009) 2603-2604.
  • J. Kim, T.Wilhelm. What is a complex graph? Physica A 387 (2008) 2637-2652.

  • T. Wilhelm. Analysis of structures causing instabilities. Phys. Rev. E 76 (2007) 011911.
  • T. Wilhelm, P. Hänggi. Power-law distributions resulting from finite resources. Physica A 329 (2003) 499-508.
    -> Our world is not just red queen, but also wu wei.
  • T. Wilhelm, R. Brüggemann. Goal functions for the development of natural systems. Ecol. Model. 132 (2000) 231-246.

         

 

   

 

 

 

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